Enoxaparin for Acute Coronary Syndromes?

obtained with the two different LMWHs; major chemical, biological and clinical differences exist between these LMWHs, and there has been much debate on this issue. We believe that pooling these data would have generated many more letters to the editor! There are few biological markers of prognosis in unstable angina. Our recent studies have focused attention on vWf as a new marker of potential interest in acute coronary syndromes. It appeared consistently as a predictive factor of outcome, and we believe it deserves attention and further evaluation in large studies. Our most recent publication demonstrated that the new anticoagulants tested in unstable angina behave better than UH with regards to vWf release. We agree it should also be confirmed. Step-by-step we are progressing in the understanding of the role of vWf in the prognosis of unstable angina, and the time has come for head-to-head comparisons between the new anticoagulant treatments. In that regard, the ARMADA study has now been completed and we will share the data very soon. I am sure that Dr. Hödl will appreciate the results.